Thermo Fisher Scientific EDG4 Polyclonal Antibody
인간 EDG4 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:20~1:50 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 40% 글리세롤 용액에 보존. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EDG4. Recombinant protein control fragment (Product # RP-90853) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640892 |
Product Specific Information
Immunogen sequence:
LLLDGLGCES CNVLAVEKYF LLLAEANSLV NAAVYSCRDA EMRRTFRRLL CCACLRQSTR ESVHYTSSAQ GGASTRIMLP ENGHPLMDST L
Sequence identity:
- Mouse: 85%
- Rat: 87%
Target Information
Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes.
In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion.
Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis.
It is also expressed in various cancer cell lines including brain, blood, breast, ovary, cervix, colon, skin, and thyroid.
ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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