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Thermo Fisher Scientific Phospho-CDK7 (Thr170) Polyclonal Antibody
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CDK7의 Thr170 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot과 IHC(Paraffin)에서 검증됨. 1 mg/mL 농도의 액상형 비결합 항체로, -20°C 보관. 전사 개시 및 DNA 복구 연구에 적합.
- 카탈로그번호
- PA538452
- 판매단위
- pk
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마지막 업데이트 2025. 08. 03. 오전 12:56
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Thermo Fisher Scientific PA538452 Phospho-CDK7 (Thr170) Polyclonal Antibody 100 ug pk판매 단위 pk ·
재고 확인 필요
688,900원VAT 포함 757,790원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-CDK7 (Thr170) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human CDK7 around the phosphorylation site of Thr170 (A-Y-TP-H-Q) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555053 |
Target Information
The trimeric complex of CDK7, cyclin H, and MNAT1 functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, involved in transcription initiation and DNA repair. This complex serves as a direct link between transcription regulation and the cell cycle. The bound complex is important in double-strand break repair in BRCA1-associated pathways. CDK7 may also be a target of germline cancer-inducing mutations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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