
Thermo Fisher Scientific CD23 Monoclonal Antibody (SP23)
CD23 단백질을 인식하는 Rabbit monoclonal antibody (Clone SP23). Western blot, IHC, Flow cytometry에 적합. Human 및 Mouse 시료 반응. Protein A로 정제된 액상 형태로, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:10–1:100 | - |
| Immunohistochemistry (IHC) | - | 11 publications |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100 | 2 publications |
| Flow Cytometry (Flow) | 1:2 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SP23 |
| Immunogen | Recombinant fragment within Human CD23 (aa 1–250). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.076 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10986348 |
Product Specific Information
The MA5-14572 immunogen is recombinant protein encoding human CD23 (amino acids 48–248).
Target Information
CD23 is a 45 kDa glycoprotein present on a subpopulation of peripheral blood and tonsil B cells and is strongly expressed on EBV-transformed B lymphoblasts. It is identical to the low-affinity IgE receptor found on B cells. CD23 expression is observed in neoplastic cells from cases of B-cell chronic lymphocytic leukemia and some centroblastic/centrocytic lymphomas. Functionally, CD23 is involved in B-cell growth, differentiation, and IgE production. A soluble form of CD23 acts as a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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