Thermo Fisher Scientific KIR2DL4 Monoclonal Antibody (2E3E12)
인간 KIR2DL4 단백질을 인식하는 마우스 단클론 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합합니다. 단백질 G로 정제된 액상 형태이며, 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E3E12 |
| Immunogen | Purified recombinant fragment of human CD158D (AA: extra 22–120) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090796 |
Target Information
CD158d / KIR2DL4 is a member of the KIR family that shares structural features with both activating and inhibitory receptors, potentially mediating different functions depending on context. It contains a cytoplasmic ITIM domain, suggesting inhibitory function, but also a transmembrane domain similar to activating KIRs. CD158d acts as an inhibitory receptor for peripheral and uterine NK cells, yet ligation with soluble mAbs can activate IFN-gamma secretion. It binds both membrane-bound and soluble forms of its ligand HLA-G.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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