Thermo Fisher Scientific DHH Polyclonal Antibody
DHH 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. Human 및 Mouse 반응성. 액상 형태, 1 mg/mL 농도, PBS + 50% glycerol 저장. 연구용으로 모폴로제네시스 관련 DHH 단백질 검출에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DHH (Accession O43323), corresponding to amino acid residues M1–G51 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899754 |
Product Specific Information
Antibody detects endogenous levels of total Dhh.
Target Information
This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis.
This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signaling activity while the C-terminal portion is involved in precursor processing.
The C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting it to the cell surface and preventing free diffusion throughout the organism.
Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy.
This protein may be involved in both male gonadal differentiation and perineurial development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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