Thermo Fisher Scientific NDUFV3 Polyclonal Antibody
Human NDUFV3 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보관됩니다. 미토콘드리아 복합체 I 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NDUFV3. Recombinant protein control fragment (Product #RP-95892) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644582 |
Product Specific Information
Immunogen sequence:
QEAQVFRGLA STVSLSAESG KSEKGQPQNS KKQSPPKKPA PVPAEPFDNT TYKNLQHHDY STYTFLDLNL ELSKFRMP
Sequence identity:
- Mouse: 62%
- Rat: 61%
Target Information
Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH produced in the Krebs cycle, this complex transfers electrons to ubiquinone, forming ubiquinol and driving subsequent electron passage through the chain, ultimately reducing oxygen to water.
Mitochondrial complex I consists of over 40 subunits, and defects in these subunits are associated with various myopathies and neuropathies.
NDUFV3 (NADH dehydrogenase [ubiquinone] flavoprotein 3), also known as NADH-ubiquinone oxidoreductase 9 kDa subunit or CI-9kD, is a 108 amino acid protein that is believed not to be directly involved in catalysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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