Thermo Fisher Scientific PPP2R2B Polyclonal Antibody
Thermo Fisher Scientific의 PPP2R2B 폴리클로날 항체는 인간 및 생쥐 단백질 인산화효소 2A의 조절 서브유닛을 표적합니다. Western blot 및 면역침강(IP)에 적합하며, 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 제품입니다. 연구용으로만 사용됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PPP2R2B Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 and 75 of Human protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Rat, Bovine, Rabbit, Pig, and Orangutan
Target Information
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases and is involved in the negative control of cell growth and division. It consists of a catalytic subunit and a constant regulatory subunit that associates with various regulatory subunits. The B regulatory subunit modulates substrate selectivity and catalytic activity.
This gene encodes the beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), characterized by cerebellar degeneration and impaired coordination of speech and movement. Multiple alternatively spliced variants encoding different isoforms have been identified. Some variants include a CAG trinucleotide repeat sequence (7–28 copies) that can expand to 66–78 copies in SCA12 cases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.