Thermo Fisher Scientific E2F1 Polyclonal Antibody
E2F1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. 면역조직화학(IHC)에 사용 가능하며 과학 연구용으로 최적화되었습니다. 0.5 mg/mL 농도의 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-TKGLFQTPYRSARN (aa 480–493) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933589 |
Product Specific Information
- Reported isoforms represent identical protein: NP_524437.2; NP_732646.1; NP_732647.1
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000
Target Information
The protein encoded by this gene is a member of the E2F family of transcription factors.
E2F family proteins regulate cell cycle progression and interact with tumor suppressor proteins.
They contain conserved domains including:
- DNA binding domain
- Dimerization domain (interacts with DP proteins)
- Transactivation domain (acidic amino acid-rich)
- Tumor suppressor association domain
- Cyclin binding domain (in E2F1, E2F2, and E2F3)
E2F1 binds preferentially to retinoblastoma protein (pRB) in a cell-cycle dependent manner, mediating both cell proliferation and p53-dependent/independent apoptosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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