Thermo Fisher Scientific CLCN3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CLCN3. Recombinant protein control fragment (Product #RP-100451). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CLCN3,uniProtId:P51790-1,ncbiNodeId:9606,antigenRange:17-78,antigenLength:818,antigenImageFileName:PA5-60802_CLCN3_P51790-1_Rabbit.svg,antigenImageFileNamePDP:PA5-60802_CLCN3_P51790-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639855

Product Specific Information

Immunogen sequence: NSITSASSDE ELLDGAGVIM DFQTSEDDNL LDGDTAVGTH YTMTNGGSIN SSTHLLDLLD EP

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.