Thermo Fisher Scientific CDSN Polyclonal Antibody
Human CDSN 단백질에 대한 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 냉동 보관 권장. 연구용으로만 사용.
- 카탈로그번호
- PA560804
- 판매단위
- pk
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CDSN. Recombinant protein control fragment (Product #RP-100042) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639629 |
Product Specific Information
- Immunogen sequence:
SALPTNDNSY RGILNPSQPG QSSSSSQTFG VSSSGQSVSS NQRPCSSDIP DSPCSGGPIV SHSGPYIPSS HSVSGGQRPV VVVVDQHGSG APG - Highest antigen sequence identity to orthologs:
- Mouse: 61%
- Rat: 31%
Target Information
This gene encodes a protein containing KELCH-1 like domains and a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner. The dissociation of these proteins in the cytoplasm allows NF-E2-related factor 2 to translocate to the nucleus, leading to expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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