Thermo Fisher Scientific PUS10 Polyclonal Antibody
Thermo Fisher Scientific의 PUS10 Polyclonal Antibody는 인간 PUS10 단백질을 인식하는 토끼 다클론 항체입니다. Western blot과 IHC(P) 분석에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 고순도 액상 포맷으로 제공되며 장기 보관 시 -20°C에서 안정적입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PUS10. Recombinant protein control fragment (Product # RP-99687) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646149 |
Product Specific Information
Immunogen sequence:
LVKQEMGKQS LSLGRDDIVQ LKEAYKWITH PLFSEELGVP IDGKSLFEVS VVFAHPETVE DCHFLAAICP DCFKPAKNKQ SVFTRMAVMK A
Antigen homology:
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 90%
Target Information
Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs.
PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable).
It acts as a modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage, and is required for progression of the apoptotic signal through intrinsic mitochondrial cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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