Thermo Fisher Scientific GCAP2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GCAP2 (GUCA1B) N-terminal region. Validated for Western blot applications. Affinity purified and supplied as a liquid in PBS with sucrose and sodium azide. Suitable for research use only.
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- PA545026
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- pk
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human GUCA1B (aa 34–83) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576531 |
Product Specific Information
- Peptide sequence: SGTLFMHEFK RFFKVTDDEE ASQYVEGMFR AFDKNGDNTI DFLEYVAALN
- Sequence homology:
- Cow: 79%
- Dog: 79%
- Guinea Pig: 79%
- Horse: 79%
- Human: 100%
- Mouse: 86%
- Rabbit: 79%
- Rat: 79%
Target Information
Guanylate cyclase-activating proteins (GCAPs) are calcium-binding proteins belonging to the calmodulin superfamily. GCAPs without calcium activate photoreceptor guanylate cyclase during light adaptation. Calcium addition or removal induces conformational changes that activate or deactivate GCAP-1 and GCAP-2. Both forms act similarly on guanylate cyclase with approximately 50% homology. GCAP-1 is mainly localized in photoreceptor outer segments, whereas GCAP-2 is found in retina samples.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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