Thermo Fisher Scientific ALDH3A1 Polyclonal Antibody
ALDH3A1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등에 사용 가능. 고순도 Affinity Chromatography 정제, PBS + sucrose buffer로 안정적 저장. 인간 ALDH3A1 C-말단 펩타이드 면역원 기반.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human ALDH3A1 (aa 236–285) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608992 |
Product Specific Information
- Peptide sequence: KFMNSGQTCV APDYILCDPS IQNQIVEKLK KSLKEFYGED AKKSRDYGRI
- Sequence homology:
- Cow: 100%
- Dog: 100%
- Guinea Pig: 100%
- Horse: 100%
- Human: 100%
- Mouse: 86%
- Rat: 93%
Target Information
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water-soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by detoxifying reactive aldehydes and through direct absorption of UV energy. However, corneas from Aldh3A1- mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may compensate for the loss of Aldh3A1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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