Thermo Fisher Scientific Phospho-HMGCR (Ser872) Polyclonal Antibody
HMGCR Ser872 인산화 상태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human, Mouse, Rat 시료에서 반응. 1 mg/mL 농도의 액상 형태로 제공되며, PBS + 50% glycerol buffer에 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-HMGCR (Ser872) Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HMGCR around the phosphorylation site of Ser872 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899217 |
Product Specific Information
This antibody detects endogenous levels of HMGCR only when phosphorylated at Ser872.
Target Information
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) is a key enzyme in the mevalonate pathway, which is critical for the biosynthesis of cholesterol and other isoprenoids. HMGCR catalyzes the conversion of HMG-CoA to mevalonate, a rate-limiting step in cholesterol production. Due to its central role in cholesterol synthesis, HMGCR is a primary target for statin drugs used to lower cholesterol levels and reduce cardiovascular disease risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.