Thermo Fisher Scientific CD79a Monoclonal Antibody (JCB117)
인간 CD79a 단백질을 인식하는 마우스 모노클로날 항체로, IHC(P) 및 유세포분석에 적합합니다. B세포 관련 질환 연구에 활용되며, 고순도 Protein A 정제 및 안정화 PBS 버퍼로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 0.5–5 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | JCB117 |
| Immunogen | Recombinant protein of human CD79a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Tosil
- Cellular location: Membrane
Target Information
CD79a is a disulphide-linked heterodimer that includes the B29 (CD79b) polypeptide. It functions as part of the B lymphocyte antigen receptor complex, associating with Ig-alpha and Ig-beta, which are essential for B-cell receptor expression and function.
CD79a appears at the pre-B cell stage and remains until the plasma cell stage, where it becomes an intracellular component. It is expressed in most acute leukemias of precursor B-cell type, B-cell lines, B-cell lymphomas, and some myelomas, but not in myeloid or T-cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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