
Thermo Fisher Scientific Human KLHL1 Synthetic Peptide
인간 KLHL1 단백질의 N말단 14개 아미노산 서열에 해당하는 합성 펩타이드로, 항체 PA5-19998의 블로킹 펩타이드로 사용 가능. 액상 형태, PBS 완충액에 0.1% BSA 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP0120
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the amino terminus of human KLHL1.
PEP-0120 can be used as a blocking peptide with polyclonal antibody PA5-19998.
Target Information
The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins.
Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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