Thermo Fisher Scientific IGFBP7 Polyclonal Antibody
IGFBP7 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot 및 IHC(P) 적용 가능하며, 인간 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었고, PBS 및 trehalose 완충액에 보관됩니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific IGFBP7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human IGFBP-rp1 Arg98–Arg277 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607716 |
Product Specific Information
- In direct ELISAs, less than 1% cross-reactivity with recombinant human IGFBP-1, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, IGFBP-6, IGFBP-L1, IGFBP-rp10 and recombinant mouse IGFBP-7 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, regulate IGF availability in body fluids and tissues, and modulate IGF binding to its receptors.
This protein binds IGF-I and IGF-II with relatively low affinity and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion.
Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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