Thermo Fisher Scientific MAP4K5 Polyclonal Antibody
MAP4K5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, IP에 사용 가능. Human 시료 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide containing a sequence corresponding to a region within amino acids 417–482 of KHS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152000 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HepG2, Molt-4, Raji
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
MAP4K5 (KHS1) is a serine/threonine kinase that belongs to the GCK family of kinases and functions as an upstream regulator of MAP kinase signaling pathways. Yeast SPS1/STE20 operates early in MAP kinase cascades essential for yeast pheromone response. In mammalian cells, MAP4K5 activates Jun kinase, suggesting a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for MAP4K5.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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