Thermo Fisher Scientific Phospho-ATF2 (Ser322) Polyclonal Antibody
ATF2 단백질의 Ser322 인산화 부위를 인식하는 폴리클로날 항체로, 사람·생쥐·랫트 시료에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용에 적합하며, 고순도 Protein A 정제 및 안정적 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Phospho-ATF2 (Ser322) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from mouse ATF2 around the phosphorylation site of Ser322 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ATF-2 (also known as CRE-BP1) is a transcription factor that binds to AP-1 and CRE DNA response elements and belongs to the ATF/CREB family of leucine zipper proteins. It interacts with various viral oncoproteins and tumor suppressors and is targeted by SAPK/JNK and p38 MAP kinase signaling pathways. Cellular stress, such as genotoxic agents, inflammatory cytokines, and UV irradiation, activates ATF-2 by phosphorylation at Thr69 and Thr71, enhancing its transcriptional activity.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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