Thermo Fisher Scientific VEGF-R2/CD309/Flk-1/KDR3 Monoclonal Antibody (DC101)
Mouse VEGFR2(KDR/Flk-1/CD309) 인식 단일클론 항체로, Western blot 및 중화·차단·경쟁 분석에 사용 가능. Rat IgG1 기반, Protein A/G 정제, 액상 형태. 4°C 보관, 연구용 전용.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 2–5 µg/mL | |
| Neutralization (Neu) | Assay-dependent | |
| Blocking Assay (BLOCK) | Assay-dependent | |
| Competition Assay (CA) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DC101 |
| Immunogen | Recombinant full-length Mouse VEGFR2 protein (FLK1, VEGF Receptor 2, UniProt ID: P35918-1, Antigen Range: 1–1345) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase that binds vascular endothelial growth factor (VEGF) with high affinity in vitro. It is expressed early in development by endothelial cell precursors. FLK1 encodes one of the two VEGF receptors, known as kinase insert domain receptor. The signaling and trafficking of this receptor are regulated by multiple factors including Rab GTPase, P2Y purine nucleotide receptor, integrin αVβ3, and T-cell protein tyrosine phosphatase. Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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