Thermo Fisher Scientific Nidogen/Entactin Monoclonal Antibody (ELM1)

Applications

ELISA (ELISA)

• Tested Dilution: 2–4 µg/mL

Immunoelectrophoresis (IE)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Antibody stability: 24 months
• Positive Control: Mouse kidney or eye tissue
• Cellular Localization: Basement membrane
• Specificity: Reacts with intact (150 kDa) nidogen and its fragments (135, 110, 100, 80 kDa)
• Cross-reactivity: Does not cross-react with other basement membrane components or fibronectin
• Entactin/Nidogen is a multi-domain basement membrane protein involved in early embryogenesis and extracellular matrix assembly (Laminin 1, Collagen IV, Proteoglycans).
• Synthesized and secreted by mesenchymal peritubular and myoepithelial cells; influences cell adhesion in an autocrine manner.
• Expressed during embryonic and fetal development exclusively in fully developed ectodermal basement membranes.
• Does not react with human.

Target Information

This gene encodes a member of the nidogen family of basement membrane glycoproteins.
The protein interacts with several other components of basement membranes and may play a role in cell interactions with the extracellular matrix.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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