Thermo Fisher Scientific EIF2B4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human eIF2b delta. Recombinant protein control fragment (Product #RP-104712). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EIF2B4,uniProtId:Q9UI10-1,ncbiNodeId:9606,antigenRange:27-104,antigenLength:523,antigenImageFileName:PA5-65254_EIF2B4_Q9UI10-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65254_EIF2B4_Q9UI10-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2665084

Product Specific Information

Immunogen sequence: VGREMTKEEKL QLRKEKKQQK KKRKEEKGAE PETGSAVSAA QCQVGPTREL PESGIQLGTP REKVPAGRSK AELRAER

Highest antigen sequence identity to the following orthologs - mouse 78%, rat 77%.

Target Information

Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.