Thermo Fisher Scientific PAAF1 Polyclonal Antibody
Thermo Fisher Scientific의 PAAF1 Polyclonal Antibody는 인간 단백질 PAAF1을 타겟으로 하는 토끼 유래 IgG 항체입니다. ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 0.1 mg/mL 농도이며, 연구용으로만 사용됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PAAF1 (Recombinant protein control fragment, Product #RP-105973) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664581 |
Product Specific Information
Immunogen sequence:
QALRKDEGEAW LSCHPPGKPS LYGSLTCQGI GLDGIPEVTA SEGFTVNEIN KKSIHISCPK ENASSKFLAP YTTFSRIHTK SITCLDISSR GGLGVSSS
- Highest antigen sequence identity to orthologs: mouse 24%, rat 24%
Target Information
PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core.
In HIV-1 infection, PAAF1 is recruited by viral Tat to the HIV-1 promoter, promoting recruitment of the 19S regulatory complex through dissociation of the proteasome 26S, which enhances provirus transcription efficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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