Thermo Fisher Scientific MSH6 Monoclonal Antibody (A4C4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

A4C4

Immunogen

Synthetic peptide corresponding to C-terminal Human MSH6 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MSH6,uniProtId:P52701-1,ncbiNodeId:9606,antigenRange:1360,antigenLength:1360,antigenImageFileName:MA5-42406_MSH6_P52701-1_House_mouse.svg,antigenImageFileNamePDP:MA5-42406_MSH6_P52701-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol, 0.2% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911547

Product Specific Information

Positive Control: Human skin tissue lysate, rat brain tissue lysate, human thyroid tissue, human colon carcinoma tissue, human skin tissue, human breast carcinoma tissue, human esophagus tissue, human placenta tissue, mouse testis tissue, mouse colon tissue, mouse placenta tissue, human gastric adenocarcinoma tissue, mouse spleen tissue, mouse small intestine tissue, K562.

Subcellular Location: Nucleus, Chromosome.

Target Information

The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage, and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and hence the prevention of skin cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.