Thermo Fisher Scientific MSH6 Monoclonal Antibody (A4C4)
MSH6 단백질을 인식하는 Mouse monoclonal antibody (clone A4C4). Western blot 및 IHC(P)에서 검증됨. Human, Mouse, Rat 시료에 반응. Protein G 정제, 2 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A4C4 |
| Immunogen | Synthetic peptide corresponding to C-terminal Human MSH6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911547 |
Product Specific Information
Positive Control:
Human skin tissue lysate, rat brain tissue lysate, human thyroid tissue, human colon carcinoma tissue, human skin tissue, human breast carcinoma tissue, human esophagus tissue, human placenta tissue, mouse testis tissue, mouse colon tissue, mouse placenta tissue, human gastric adenocarcinoma tissue, mouse spleen tissue, mouse small intestine tissue, K562.
Subcellular Location:
Nucleus, Chromosome.
Target Information
The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and contributing to the prevention of skin cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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