Thermo Fisher Scientific Glutamine Synthetase Monoclonal Antibody (A3G2)
Glutamine Synthetase 단백질을 인식하는 Mouse Monoclonal Antibody (Clone A3G2). WB, IHC, Flow Cytometry에 적합. 인간 및 마우스 반응성. Protein G 정제, 2 mg/mL 농도, 안정적 액상 형태로 제공.
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Thermo Fisher Scientific Glutamine Synthetase Monoclonal Antibody (A3G2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A3G2 |
| Immunogen | Recombinant protein within human Glutamine synthetase aa 190–373 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911549 |
Product Specific Information
- Positive Control: SK-Br-3 cell lysate, 293 cell lysate, human liver tissue, mouse liver tissue, THP-1
- Subcellular Location: Microsome, Cytosol, Mitochondrion, Cell membrane
Target Information
Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays a central role in mammalian nitrogen flow, serving as both a nitrogen donor and acceptor. It also regulates neurotransmitter glutamate metabolism. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. GS activity is controlled by adenylylation and is decreased in the cerebral cortex of brains affected by Alzheimer’s disease, particularly near senile plaques, and under glucose deprivation conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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