
Thermo Fisher Scientific STIM1 Polyclonal Antibody
STIM1 단백질을 인식하는 염소 유래 다클론 항체로, Western blot 및 유세포분석에 사용 가능. 인간 시료 반응성, 비결합형 액상 형태. 고순도 정제 및 안정적 저장 조건 제공. 연구용으로만 사용.
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Thermo Fisher Scientific STIM1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-YIQNRYSKEHMKK (aa 231–243) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932897 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. The precise mechanism of STIM1–Orai1 interaction has not been fully elucidated. STIM1 also associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-142243_STIM1_Q13586-1_Goat.svg)
(이미지: PA5-142243_STIM1_Q13586-1_Goat_PDP.jpeg)
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