Thermo Fisher Scientific FGFR2 Monoclonal Antibody (OTI1H5), TrueMAB
FGFR2 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC에 적합합니다. 인간 시료에 반응하며, 동결건조 형태로 제공됩니다. 고순도의 친화 크로마토그래피 정제 제품으로 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H5 |
| Immunogen | Full length human recombinant protein of human FGFR2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
FGFR2 (Fibroblast Growth Factor Receptor 2) is a receptor tyrosine kinase that regulates various cellular processes including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, differentiation, and tissue repair.
It is implicated in diseases such as cancer, rheumatoid arthritis, and diabetic retinopathy.
Mutations in FGFR2 are associated with Crouzon, Pfeiffer, Apert, Jackson-Weiss, Beare-Stevenson, Saethre-Chotzen syndromes, and syndromic craniosynostosis.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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