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Thermo Fisher Scientific Claudin 2 Polyclonal Antibody (MH44)

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Claudin-2 단백질을 인식하는 Thermo Fisher Scientific의 다클론성 항체로, 인간·개·쥐 시료에 반응합니다. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제된 고품질 제품입니다. 연구용으로만 사용 가능합니다.

카탈로그번호: 516100
브랜드: Thermo Fisher Scientific
카테고리: Polyclonal Antibodies
판매단위: pk

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마지막 업데이트 2025. 08. 04. 오전 05:43

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Thermo Fisher Scientific 516100 Claudin 2 Polyclonal Antibody (MH44) 100 ug pk판매 단위 pk ·

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605,100원VAT 포함 665,610원

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Thermo Fisher Scientific · Thermo Fisher Scientific Claudin 2 Polyclonal Antibody (MH44)

Thermo Fisher Scientific Claudin 2 Polyclonal Antibody (MH44)

Applications and Tested Dilutions

Application	Tested Dilution	Publications
Western Blot (WB)	0.25 - 2 µg/mL	64
Immunohistochemistry (IHC)	Assay-dependent	21
Immunohistochemistry (Paraffin) (IHC (P))	-	2
Immunohistochemistry (Frozen) (IHC (F))	-	4
Immunocytochemistry (ICC/IF)	1:100	43
Flow Cytometry (Flow)	-	1
ELISA	0.1 - 1.0 µg/mL	1
Immunoprecipitation (IP)	-	4
Miscellaneous PubMed (Misc)	-	3

Product Specifications

Specification	Description
Species Reactivity	Dog, Human, Rat
Published Species	Dog, Fish, Human, Mouse, Non-human primate, Pig, Rabbit, Rat, Sheep
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Clone	MH44
Immunogen	Synthetic peptide derived from the C-terminus of the human Claudin-2 protein
Conjugate	Unconjugated
Form	Liquid
Concentration	0.25 mg/mL
Purification	Antigen affinity chromatography
Storage Buffer	PBS, pH 7.4
Contains	0.1% sodium azide
Storage Conditions	-20°C
Shipping Conditions	Ambient (domestic); Wet ice (international)
RRID	AB_2533911

Product Specific Information

This antibody is specific for the ~22 kDa Claudin-2 protein and does not appear to cross-react with related endogenous proteins. Reactivity was confirmed by western blotting with rat kidney and by immunostaining of rat small intestine. This antibody is confirmed reactive with human, rat, and dog Claudin-2. The reactivity with other species has not been determined.

Target Information

Tight junctions are specialized regions of cell-cell contact, abundant in luminal epithelial sheets. These junctions function as molecular gaskets preventing leakage of ions and molecules between cells. They also maintain epithelial polarity by blocking diffusion of membrane proteins between apical and basolateral surfaces. Claudin-1 and Claudin-2 are key structural components of tight junction strands, connecting to the actin cytoskeleton through ZO-1. Claudin-2 acts as a paracellular channel with cation (Na⁺) selectivity, mainly expressed in liver and kidney, with minor presence in brain.