Thermo Fisher Scientific Axiom Canine Genotyping Array Set A

Applied Biosystems™ Axiom Canine Genotyping Array Set A

Axiom™ Canine Genotyping Array Sets A and B were designed as part of the Expert Array Design program. These arrays provide access to approximately 1.1 million markers discovered by the National Human Genome Research Institute of the NIH. The content, distributed over two arrays, enables dense genotyping for validation and discovery of variants associated with specific phenotypes. All new content was discovered through high-quality sequencing of over 300 dog genomes and aligned with the CanFam3 reference genome.

Canis familiaris serves as a valuable model organism for understanding human disease and drug discovery. Axiom canine genotyping arrays allow dense genotyping to isolate variants associated with specific phenotypes. Understanding these genotypes helps breeders anticipate offspring traits, minimize inbreeding, and screen for potential genetic disorders.

Features of Axiom Canine Genotyping Array Set A

This array includes over 460,000 markers and legacy content from in-market arrays, along with new rare variants. It provides continuity for existing studies while adding access to new functional variants.

• Markers from legacy in-market genotyping arrays
• Functional variants of biological relevance
• Intergenic variants based on newly available long non-coding RNA (lncRNA) data
• miRNA variants
• Breed-specific markers

Learn more about Canine Array Set B ›

Applications

• Genome-wide association studies (GWAS)
• Veterinary research
• Direct-to-consumer genetic testing
• Model organism studies for complex human diseases such as cancer and diabetes

Data from the Axiom Canine Genotyping Arrays are analyzed using
Axiom Analysis Suite
and
Axiom CNV Summary Tools Software.
Automated genotyping analysis enables accurate results across various breeds, including those with inbreeding characteristics common in canine populations.

제품 사양