Thermo Fisher Scientific MORF4 Monoclonal Antibody (OTI5A6), TrueMAB
인간 MORF4 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot에 적합합니다. 1 mg/mL 농도의 액상 제품이며, PBS/BSA/glycerol 완충액에 보관됩니다. 세포 노화 관련 전사 억제 연구용으로 사용됩니다.
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Thermo Fisher Scientific MORF4 Monoclonal Antibody (OTI5A6), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5A6 |
| Immunogen | Human recombinant protein fragment (aa 1–255 of MORF4) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cellular senescence is the terminal non-dividing state that normal cells enter after completing their proliferative potential. Fusions of immortal human cell lines have led to classification into four complementation groups. Mortality factor 4 (MORF4) is the lead member of a family of transcription factor-like proteins that reverses the immortal phenotype. MORF4 localizes to the nucleus and contains transcription factor-like motifs such as helix-loop-helix and leucine zipper, enabling formation of transcriptionally active homo- or heterodimers. MORF4 binds to transcription corepressors mSin3A and TLE, suggesting a role in transcriptional repression of genes involved in cellular senescence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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