Thermo Fisher Scientific Human KappaB ras2 Synthetic Peptide
인간 KappaB ras2 단백질의 C-말단 14개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20342의 블로킹 펩타이드로 사용 가능. NF-kappa-B 경로 연구용으로 적합. 액상 형태, 200 µg/mL 농도, -20°C 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human KappaB ras-2.
PEP-0462 can be used as a blocking peptide with polyclonal antibody PA5-20342.
Target Information
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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