Thermo Fisher Scientific Human KappaB ras1 Synthetic Peptide
Human KappaB ras-1의 C-말단 15개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20341의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 PBS(pH 7.2), 0.1% BSA, 0.02% sodium azide 포함. -20°C 보관.
- 카탈로그번호
- PEP0461
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human KappaB ras-1.
PEP-0461 can be used as a blocking peptide with polyclonal antibody PA5-20341.
Target Information
KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are small Ras-like GTPase proteins that associate with Ikappa-B, an inhibitor of NF-kappa-B.
Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta. Ikappa-B-beta contains a unique 47-amino acid region within its ankyrin domain.
Inactive Ikappa-B-alpha–NF-kappa-B complexes can shuttle between nucleus and cytoplasm, while Ikappa-B-beta–NF-kappa-B complexes are retained in the cytoplasm.
KappaB-ras proteins preferentially bind to the Ikappa-B-beta form through this unique insert, modulating its localization and degradation rate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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