Thermo Fisher Scientific Human PD-L1 Synthetic Peptide
Human PD-L1 합성 펩타이드로, 항체 PA5-20343의 블로킹 펩타이드로 사용 가능. 액상 형태이며 PBS(pH 7.2) + 0.1% BSA, 0.02% sodium azide 포함. 인간 PD-L1 단백질 연구에 적합. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Miscellaneous PubMed (Misc)
- Publications available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human PD-L1.
PEP-0463 can be used as a blocking peptide with polyclonal antibody PA5-20343.
Target Information
Programmed death receptor ligand 1 (PD-L1, also known as B7-H1) is a member of the B7 family.
Its receptor, programmed death receptor 1 (PD-1), negatively regulates T-cell receptor (TCR) signaling.
Upon binding PD-1, PD-L1 can decrease TCR-mediated proliferation and cytokine production.
PD-L1 is abundantly expressed on many murine and human cancers and can be upregulated by IFN-gamma stimulation.
Thus, PD-L1 may play a critical role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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