Thermo Fisher Scientific Tubulin alpha-1B Polyclonal Antibody
Tubulin alpha-1B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. WB, IHC, ICC/IF에 사용 가능하며, 다양한 종에 반응합니다. 고순도 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 118–365 (P68363) of alpha Tubulin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11157253 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2, NIH-3T3
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (99%), Xenopus laevis (98%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Microtubules are intracellular dynamic polymers composed of alpha/beta-tubulin heterodimers and microtubule-associated proteins (MAPs). They exhibit intrinsic polarity, with highly dynamic plus ends and less dynamic minus ends. Microtubules are essential for mitosis, meiosis, cell shape maintenance, intracellular transport, and cell motility via flagella and cilia.
In mammalian cells, microtubules have minus ends anchored in microtubule organizing centers (MTOCs). GTP is required for tubulin heterodimer association and microtubule formation. Microtubule polymerization is reversible, and dynamic instability describes the alternating growth and shortening of microtubules.
Alpha-tubulin (~50 kDa) exists as part of soluble alpha/beta-tubulin dimers or polymerized microtubules. In humans, six genes encode alpha-tubulin classes.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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(이미지 파일: PA5-21979_Tubulin_alpha-1B_P68363-1_Rabbit.svg, PA5-21979_Tubulin_alpha-1B_P68363-1_Rabbit_PDP.jpeg)
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