Thermo Fisher Scientific Kir3.1 (KCNJ3) Polyclonal Antibody
Kir3.1(KCNJ3) 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB 및 IHC(P) 분석에 적합. 인간 및 생쥐 반응성 확인. 고순도 항원 친화 크로마토그래피 정제. 안정한 액상 형태로 장기 보관 가능.
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Thermo Fisher Scientific Kir3.1 (KCNJ3) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 248–501 of GIRK1 (Uniprot ID: P48549) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal, 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11155445 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (98%), Rat (98%), Chicken (91%), Rhesus Monkey (100%), Bovine (99%), Guinea pig (99%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
This potassium channel is controlled by G proteins. Inward rectifier potassium channels allow potassium to flow more easily into the cell than out of it. Their voltage dependence is regulated by extracellular potassium concentration; as external potassium increases, the voltage range of channel opening shifts to more positive voltages. The inward rectification mainly results from blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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