Thermo Fisher Scientific Cathelicidin Polyclonal Antibody
인간 및 생쥐 Cathelicidin 단백질을 검출하는 Rabbit Polyclonal Antibody. Western blot과 IHC(P)에서 검증됨. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 재현성을 제공. 연구용으로 감염 및 면역 반응 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAMP (Accession P49913), corresponding to amino acid residues I43–S93 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851858 |
Product Specific Information
Antibody detects endogenous levels of total Cathelicidin.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils. Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. These molecules are essential for defense against invasive bacterial infection in skin. Beyond direct antimicrobial activity, Cathelicidins play multiple roles in innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, neutrophil chemotaxis, and mast cell recruitment. Cathelicidin antimicrobial peptides are considered prototypes for innovative drugs targeting infection and immune modulation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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