Thermo Fisher Scientific PTHLH Polyclonal Antibody
PTHLH 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF 등 다양한 응용에 사용 가능. 고순도 친화 크로마토그래피 정제 제품으로, 인간·마우스·랫트 반응성. 연구용으로만 사용.
- 카탈로그번호
- PA5102455
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PTHLH (Accession P12272), corresponding to amino acid residues T75–K125 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851860 |
Product Specific Information
Antibody detects endogenous levels of total PTHLH.
Target Information
The protein encoded by this gene belongs to the parathyroid hormone family. It regulates endochondral bone development and epithelial-mesenchymal interactions during mammary gland and tooth formation.
This hormone is involved in lactation, possibly by regulating calcium mobilization and transfer to milk.
Its receptor, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy.
Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
There is evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, producing nuclear forms of this hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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