Thermo Fisher Scientific RASA1 Polyclonal Antibody
RASA1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot과 IHC(P)에서 검증됨. 인간, 마우스, 랫트 시료에 반응하며, 친화 크로마토그래피로 정제된 액상 항체. 연구용으로만 사용 가능.
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- PA5102451
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RASA1 (Accession P20936), corresponding to amino acid residues V956–S1006. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851856 |
Product Specific Information
Antibody detects endogenous levels of total RASA1.
Target Information
TACC1 is located on the 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members (TACC1, TACC2, and TACC3) map very closely to the corresponding FGFR1, FGFR2, and FGFR3 genes on chromosomes 4, 8, and 10. Since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. TACC1 contains a conserved C-terminal region similar to the Drosophila homolog D-TACC, which is necessary for normal spindle function, and mammalian TACC proteins appear to interact with centrosomes and microtubules in a similar manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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