Thermo Fisher Scientific Dynactin 1 Monoclonal Antibody (6B11)
Dynactin 1 단백질을 특이적으로 인식하는 Mouse 모노클로날 항체로, Western blot 및 Immunoprecipitation에 적합. Human 시료 반응성 검증 완료. 항원 친화 크로마토그래피로 고순도 정제. 연구용으로만 사용 가능.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:1,750 | View 1 publication |
| Immunoprecipitation (IP) | 1:50–1:200 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6B11 |
| Immunogen | Synthetic peptide corresponding to the N-terminal of human Dynactin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2539681 |
Product Specific Information
- Detects endogenous levels of DCTN1 (Dynactin 1) at ~150 kDa.
- No cross-reactivity with related proteins.
- Purity >95% confirmed by SDS-PAGE.
Target Information
The Dynactin 1 gene encodes the largest subunit of the dynactin complex, which consists of 10 subunits ranging from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in various cellular processes such as:
- ER-to-Golgi transport
- Centripetal movement of lysosomes and endosomes
- Spindle formation and chromosome movement
- Nuclear positioning and axonogenesis
This subunit interacts directly with the dynein intermediate chain and binds microtubules via a conserved CAP-Gly domain in its N-terminus.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Mutations in this gene are associated with distal hereditary motor neuronopathy type VIIB (HMN7B), also known as distal spinal and bulbar muscular atrophy (dSBMA).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Calumenin Monoclonal Antibody (6B4)
783,000원
Thermo Fisher Scientific
Thermo Fisher Scientific ID1 Monoclonal Antibody (3A9)
565,000원
Thermo Fisher Scientific
Thermo Fisher Scientific Dynactin 1 Monoclonal Antibody (6B11)
738,100원
Thermo Fisher Scientific
Thermo Fisher Scientific ARID5A Monoclonal Antibody (P921)
641,300원
Thermo Fisher Scientific
Thermo Fisher Scientific LIN7A Monoclonal Antibody (P879)
673,500원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|