Thermo Fisher Scientific Calumenin Monoclonal Antibody (6B4)
Calumenin 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6B4 |
| Immunogen | Synthetic peptide corresponding to amino acids at the C-terminus of human Calumenin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2539685 |
Product Specific Information
This antibody detects endogenous Calumenin protein at approximately 45 kDa, although the predicted molecular weight is 37 kDa.
Purity is greater than 95% as determined by SDS-PAGE.
Target Information
Calumenin is a 315 amino acid calcium-binding member of the CREC EF-hand protein family. It is a secreted protein located in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus.
Calumenin contains six Ca²⁺-binding (EF-hand) motifs and interacts with serum amyloid P component (SAP) in the presence of calcium. Together, they may play roles in immunological defense and amyloidosis.
Calumenin inhibits the vitamin K-dependent γ-carboxylation system, potentially affecting thrombosis and wound healing through autocrine or paracrine mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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