Thermo Fisher Scientific ACVR1 Polyclonal Antibody
ACVR1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. 인간 및 마우스에 반응하며, IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제된 액상 항체로, 장기 보관 시 -20°C에서 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:100–1:1,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Activin A Receptor type I |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.41 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792406 |
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (93%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Activin A receptor, type I (ACVR1) belongs to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.
ACVR1 signals a specific transcriptional response in concert with activin type II receptors.
The ACVR1 gene encodes activin A type I receptor, which signals a particular transcriptional response in concert with activin type II receptors.
Mutations in ACVR1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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