ELK Biotechnology MEK-4 (phospho Ser80) rabbit pAb
MEK-4 (phospho Ser80) rabbit pAb는 MAPK 신호전달 연구용 항체로, 인산화된 Ser80 부위를 인식합니다. WB, IHC, IF, ELISA에 사용 가능하며, 인간, 마우스, 랫트 시료에 반응합니다. 세포 내 MAPK 경로 분석 및 신호전달 연구에 적합합니다.
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MEK-4 (phospho Ser80) rabbit pAb
제품 개요
MEK-4 (phospho Ser80) rabbit pAb는 인간 SEK1/MKK4의 Ser80 인산화 부위를 인식하는 폴리클로날 항체입니다. MAPK 경로 연구 및 세포 내 신호전달 분석에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | MEK-4 (phospho Ser80) rabbit pAb |
| Alternative Names | MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; MAPKK 4; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated protein kinase 1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human SEK1/MKK4 around phosphorylation site of Ser80 (AA range: 46–95) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 44 kD |
| GeneID (Human) | 6416 |
| Human Swiss-Prot No | P45985 |
| Cellular Localization | Cytoplasm, Nucleus |
| Storage | -20°C, 1 year |
| Host | Rabbit |
Background
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as integration points for multiple biochemical signals and are involved in diverse cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated by MAPKKKs and subsequently phosphorylates downstream MAPK targets. A similar protein in mouse is implicated in liver organogenesis. A pseudogene is located on the X chromosome, and multiple transcript variants exist due to alternative splicing.
[Provided by RefSeq, Jul 2013]
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