ELK Biotechnology C/EBP β (phospho Thr235) rabbit pAb
C/EBP β (phospho Thr235) rabbit polyclonal antibody로, 인산화 Thr235 부위 인식. WB, IHC, IF, ELISA에 사용 가능. 핵 및 세포질에서 발현되는 전사인자 검출에 적합. 인간, 마우스, 랫트 반응성.
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제품명
C/EBP β (phospho Thr235) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CEBPB; LAP; TCF5; PP9092; CCAAT/enhancer-binding protein beta; C/EBP beta; Liver activator protein; Nuclear factor NF-IL6; Transcription factor 5; TCF-5 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human C/EBP-beta around the phosphorylation site of Thr235/188 (AA range: 201–250) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kDa |
| Gene ID (Human) | 1051 |
| Human Swiss-Prot No. | P17676 |
| Cellular Localization | Nucleus, Cytoplasm. Translocates to the nucleus when phosphorylated at Ser-288. In T-cells, when sumoylated, drawn to pericentric heterochromatin allowing proliferation (By similarity). |
| Species Reactivity | Human, Mouse, Rat |
Background
This intronless gene encodes a transcription factor containing a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Its activity is important in regulating genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms with distinct biological functions.
[Provided by RefSeq, Oct 2013]
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