
Thermo Fisher Scientific CRYBB2 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 CRYBB2 폴리클로날 항체로, Western blot에 적합합니다. 정제된 Rabbit IgG 항체이며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 안정적인 저장을 위해 PBS 및 글리세롤 완충액에 보관됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human CRYBB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2717314 |
Product Specific Information
The antibody was affinity-purified from mouse ascites by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Crystallins are divided into two major classes: taxon-specific (enzyme) and ubiquitous. The ubiquitous class constitutes the major structural proteins of the vertebrate eye lens, maintaining transparency and refractive index.
During lens development, central fiber cells lose their nuclei, so crystallins synthesized early are retained for life, making them highly stable.
Mammalian crystallins are categorized into alpha, beta, and gamma families. Beta-crystallins, the most heterogeneous, can form homo- or heterodimers and aggregates.
The CRYBB2 gene encodes a beta basic group member and is clustered with beta-A4, beta-B1, and beta-B3 genes. Mutations in CRYBB2 have been associated with type 2 cerulean cataracts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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