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Thermo Fisher Scientific GTPase HRAS Polyclonal Antibody, FITC
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Thermo Fisher Scientific GTPase HRAS Polyclonal Antibody, FITC

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FITC로 표지된 HRAS 단백질에 특이적인 토끼 폴리클로날 항체. Western blot, ELISA, IP에 사용 가능. 인간, 생쥐, 닭 반응성. 합성 펩타이드(aa 100-150) 면역원 사용. 형광 분석용으로 적합하며 -20°C 어두운 곳에 보관.

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P21RAS-112-FITC
판매단위
pk
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마지막 업데이트 2025. 08. 02. 오전 03:44
Thermo Fisher Scientific P21RAS-112-FITC GTPase HRAS Polyclonal Antibody, FITC 200 ul pk판매 단위 pk ·
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594,400원VAT 포함 653,840원

Thermo Fisher Scientific · Thermo Fisher Scientific GTPase HRAS Polyclonal Antibody, FITC

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:500–1:1,000
ELISA 1:10,000
Immunoprecipitation (IP) 1:50–1:250

Product Specifications

항목 내용
Species Reactivity Chicken, Human, Mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide within amino acid region 100–150 of human GTPase HRAS protein
Conjugate FITC
Excitation / Emission Max 498 / 517 nm
Form Liquid
Concentration 0.5–1.5 mg/mL
Purification Affinity chromatography
Storage Buffer Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA
Contains 0.02% sodium azide
Storage Conditions −20°C, store in dark
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

Monomeric G protein Ras acts as a molecular switch linking receptor and nonreceptor tyrosine kinase activation to multiple downstream signaling pathways that regulate cytoplasmic and nuclear events. Mammalian cells contain three Ras proto-oncogenes encoding closely related proteins: H-, K-, and N-Ras. Oncogenic Ras mutations occur in approximately 30% of human cancers. Constitutive Ras activation leads to increased proliferation and reduced apoptosis.

  • K-Ras mutations: Common in pancreatic, colorectal, and non-small-cell lung carcinomas
  • H-Ras mutations: Common in bladder, kidney, and thyroid carcinomas
  • N-Ras mutations: Found in melanoma, hematologic malignancies, and hepatocellular carcinoma

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.

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