Thermo Fisher Scientific Human PLK4, GST Tag Recombinant Protein

Thermo Fisher Scientific Human PLK4, GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

For maximum recovery, please spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use materials from original packaging until exhausted.
For larger sizes, aliquoting may reduce freeze/thaw cycles; avoid aliquots below 20 µL.
Do not store kinase diluted.
Properly stored at -80°C, product stability is guaranteed for 6 months from purchase.

Recombinant human PLK4 (1–836) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Features:

• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes for convenient use

Related Product:
LanthaScreen™ Eu Kinase Binding Assay

Protein Form: Recombinant, Fragment
Gene Accession Number: NP_055079.3

Target Information

PLK4 (Polo-like kinase 4) is a serine/threonine protein kinase that localizes to centrioles and regulates centriole duplication during the cell cycle. Overexpression induces multiple procentrioles around existing centrioles, leading to centriole amplification and Plk4-induced centriole biogenesis. Reduced PLK4 expression increases mitotic error risk and cancer development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.