Thermo Fisher Scientific KCNN3 Polyclonal Antibody
KCNN3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC(F), ICC/IF 등 다양한 응용에 적합. Lyophilized 형태로 제공되며 -20°C에서 보관. 신경 흥분성 조절 관련 연구용으로 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide DTSGHFHDSGVGDLDEDPKC, corresponding to amino acid residues 2–21 of human KCa2.3 (SK3) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736015 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and mediated by different calcium-activated potassium channels.
KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein forming a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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