Thermo Fisher Scientific Phospho-STING (Ser365) Polyclonal Antibody
Phospho-STING (Ser365) 폴리클로날 항체로 인간 및 생쥐 시료에 반응합니다. Western blot 및 ELISA에 적합하며, STING 신호전달 경로 연구에 활용됩니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S365 of mouse STING (NP_0825371) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.63 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901901 |
Product Specific Information
- Positive Samples: THP-1
- Immunogen sequence: LISGMD
Target Information
STING is a 379 amino acid signaling protein that plays a crucial role in innate immune signaling. It activates NF-κB and IRF3 transcription pathways to induce type I interferons (IFN-α, IFN-β), establishing an antiviral state. STING may also function as a translocon influencing interferon induction and is involved in apoptotic signal transduction via association with MHC-II. It is localized in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across tissues.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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