Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI4E2), TrueMAB
PARP16 단백질을 인식하는 Thermo Fisher의 단클론 항체로, Flow Cytometry에 적합합니다. Human 시료 반응성이 있으며, Affinity chromatography로 정제된 액상 형태입니다. -20°C 보관, 연구용 전용 제품입니다.
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- TA500453
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E2 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human PARP16 expression vector |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells.
PARP16 is a member of the poly(ADP-ribose) polymerases (PARPs) family encoded by different genes and displaying a conserved catalytic domain. PARP-1 (113 kDa) and PARP-2 (62 kDa) are the founding members whose catalytic activity is stimulated by DNA strand breaks.
The expanding repertoire of PARPs extends the field of poly(ADP-ribosyl)ation reactions to various aspects of cell biology, including cell proliferation and cell death. Some members interact with each other, share common partners, and localize similarly within cells, suggesting fine-tuned regulation of this post-translational modification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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