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Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI2C8), TrueMAB
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Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI2C8), TrueMAB

상품 한눈에 보기

PARP16 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 적합합니다. Human 종에 반응하며, 0.45 mg/mL 농도의 액상 형태로 제공됩니다. Affinity chromatography로 정제되었으며, 연구용으로만 사용 가능합니다.

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pk
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Thermo Fisher Scientific TA500452 PARP16 Monoclonal Antibody (OTI2C8), TrueMAB 100 ul pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI2C8), TrueMAB

Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI2C8), TrueMAB

Applications

  • Flow Cytometry (Flow)

Tested Dilution

  • 1:100

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone OTI2C8
Immunogen Full-length protein expressed in 293T cell transfected with human PARP16 expression vector
Conjugate Unconjugated
Form Liquid
Concentration 0.45 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of the poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displays a conserved catalytic domain. PARP-1 (113 kDa) and PARP-2 (62 kDa) are known to have catalytic activity stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs extends the field of poly(ADP-ribosyl)ation reactions to various aspects of cell biology, including cell proliferation and cell death. Some new members interact with each other, share common partners and subcellular localizations, suggesting possible fine-tuning in the regulation of this post-translational modification of proteins.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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