Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI2C8), TrueMAB
PARP16 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 적합합니다. Human 종에 반응하며, 0.45 mg/mL 농도의 액상 형태로 제공됩니다. Affinity chromatography로 정제되었으며, 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PARP16 Monoclonal Antibody (OTI2C8), TrueMAB
Applications
- Flow Cytometry (Flow)
Tested Dilution
- 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C8 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human PARP16 expression vector |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of the poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displays a conserved catalytic domain. PARP-1 (113 kDa) and PARP-2 (62 kDa) are known to have catalytic activity stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs extends the field of poly(ADP-ribosyl)ation reactions to various aspects of cell biology, including cell proliferation and cell death. Some new members interact with each other, share common partners and subcellular localizations, suggesting possible fine-tuning in the regulation of this post-translational modification of proteins.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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